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Classifying kinase conformations using a machine learning approach

BACKGROUND: Signaling proteins such as protein kinases adopt a diverse array of conformations to respond to regulatory signals in signaling pathways. Perhaps the most fundamental conformational change of a kinase is the transition between active and inactive states, and defining the conformational f...

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Detalles Bibliográficos
Autores principales:	McSkimming, Daniel Ian, Rasheed, Khaled, Kannan, Natarajan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290640/ https://www.ncbi.nlm.nih.gov/pubmed/28152981 http://dx.doi.org/10.1186/s12859-017-1506-2

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