Cargando…

Chemosensitizing Effect of Astragalus Polysaccharides on Nasopharyngeal Carcinoma Cells by Inducing Apoptosis and Modulating Expression of Bax/Bcl-2 Ratio and Caspases

BACKGROUND: Platinum-based chemotherapy is the most effective regimen for nasopharyngeal carcinoma, which presents highly invasive and metastatic activity. However, the dose-related toxicity of chemotherapy agents limits the dose administration. Astragalus polysaccharide (APS) is the major active in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhou, Zhen, Meng, Minhua, Ni, Haifeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2017
Materias:	Lab/In Vitro Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291085/ https://www.ncbi.nlm.nih.gov/pubmed/28124680 http://dx.doi.org/10.12659/MSM.903170

Ejemplares similares

Boschniakia Rossica Polysaccharide Triggers Laryngeal Carcinoma Cell Apoptosis by Regulating Expression of Bcl-2, Caspase-3, and P53
por: Yao, Chunping, et al.
Publicado: (2017)

Angiotensin II-Induced Apoptosis of Human Umbilical Vein Endothelial Cells was Inhibited by Blueberry Anthocyanin Through Bax- and Caspase 3-Dependent Pathways
por: Du, Jian, et al.
Publicado: (2016)

The Effects of Astragalus Polysaccharide on Bone Marrow-Derived Mesenchymal Stem Cell Proliferation and Morphology Induced by A549 Lung Cancer Cells
por: Zhang, Yue-Mei, et al.
Publicado: (2019)

WNT974 Inhibits Proliferation, Induces Apoptosis, and Enhances Chemosensitivity to Doxorubicin in Lymphoma Cells by Inhibiting Wnt/β-Catenin Signaling
por: Chen, Senmin, et al.
Publicado: (2020)

Astragalus Polysaccharide Inhibits Ionizing Radiation-Induced Bystander Effects by Regulating MAPK/NF-κB Signaling Pathway in Bone Mesenchymal Stem Cells (BMSCs)
por: Zhang, Liying, et al.
Publicado: (2018)

miR-143 Induces the Apoptosis of Prostate Cancer LNCap Cells by Suppressing Bcl-2 Expression
por: Ma, Zhiwei, et al.
Publicado: (2017)

Down-Regulation of MicroRNA-133b Suppresses Apoptosis of Lens Epithelial Cell by Up-Regulating BCL2L2 in Age-Related Cataracts
por: Zhang, Feng, et al.
Publicado: (2016)

Impact of Mitochondria-Mediated Apoptosis in U251 Cell Cycle Arrest in G1 Stage and Caspase Activation
por: Zhang, Lei, et al.
Publicado: (2015)

Astragalus and Baicalein Regulate Inflammation of Mesenchymal Stem Cells (MSCs) by the Mitogen-Activated Protein Kinase (MAPK)/ERK Pathway
por: Zhu, Lei, et al.
Publicado: (2017)

MicroRNA-365 Inhibits Cell Growth and Promotes Apoptosis in Melanoma by Targeting BCL2 and Cyclin D1 (CCND1)
por: Zhu, Yong, et al.
Publicado: (2018)

Expression of NLPR3 in Psoriasis Is Associated with Enhancement of Interleukin-1β and Caspase-1
por: Su, Fei, et al.
Publicado: (2018)

Artemether Regulates Chemosensitivity to Doxorubicin via Regulation of B7-H3 in Human Neuroblastoma Cells
por: Tan, Wei-Qiang, et al.
Publicado: (2017)

Mukonal Inhibits Cell Proliferation, Alters Mitochondrial Membrane Potential and Induces Apoptosis and Autophagy in Human CNE1 Nasopharyngeal Carcinoma Cells
por: Guo, Yingyuan, et al.
Publicado: (2019)

Cantharidin Inhibits Anti-Apoptotic Bcl-2 Family Proteins and Induces Apoptosis in Human Osteosarcoma Cell Lines MG-63 and MNNG/HOS via Mitochondria-Dependent Pathway
por: Feng, Shoumin, et al.
Publicado: (2018)

Knockdown of High Mobility Group-Box 3 (HMGB3) Expression Inhibits Proliferation, Reduces Migration, and Affects Chemosensitivity in Gastric Cancer Cells
por: Guo, Shengnan, et al.
Publicado: (2016)

Costunolide Inhibits the Growth of OAW42-A Multidrug-Resistant Human Ovarian Cancer Cells by Activating Apoptotic and Autophagic Pathways, Production of Reactive Oxygen Species (ROS), Cleaved Caspase-3 and Cleaved Caspase-9
por: Fang, Yichen, et al.
Publicado: (2019)

Expression of TP53, BCL-2, and VEGFA Genes in Esophagus Carcinoma and its Biological Significance
por: Wei, Wei, et al.
Publicado: (2015)

microRNA-205 and microRNA-338-3p Reduces Cell Apoptosis in Prostate Carcinoma Tissue and LNCaP Prostate Carcinoma Cells by Directly Targeting the B-Cell Lymphoma 2 (Bcl-2) Gene
por: Zhang, Xi, et al.
Publicado: (2019)

α-Pinene Induces Apoptotic Cell Death via Caspase Activation in Human Ovarian Cancer Cells
por: Hou, Jing, et al.
Publicado: (2019)

Naturally Occurring Sesquiterpene Lactone-Santonin, Exerts Anticancer Effects in Multi-Drug Resistant Breast Cancer Cells by Inducing Mitochondrial Mediated Apoptosis, Caspase Activation, Cell Cycle Arrest, and by Targeting Ras/Raf/MEK/ERK Signaling Pathway
por: Wu, Zhiqiang, et al.
Publicado: (2019)

Naturally Occurring Sclareol Diterpene Augments the Chemosensitivity of Human Hela Cervical Cancer Cells by Inducing Mitochondrial Mediated Programmed Cell Death, S-Phase Cell Cycle Arrest and Targeting Mitogen-Activated Protein Kinase (MAPK)/Extracellular-Signal-Regulated Kinase (ERK) Signaling Pathway
por: Li, Wang, et al.
Publicado: (2020)

Bcl-2 19-kDa Interacting Protein 3 (BNIP3)-Mediated Mitophagy Attenuates Intermittent Hypoxia-Induced Human Renal Tubular Epithelial Cell Injury
por: Zhang, Xiao-Bin, et al.
Publicado: (2022)

Receptor-Interacting Protein 3/Caspase-8 May Regulate Inflammatory Response and Promote Tissue Regeneration in the Periodontal Microenvironment
por: Yan, Bingbing, et al.
Publicado: (2018)

Optimized Extraction, Preliminary Characterization, and In Vitro Antioxidant Activity of Polysaccharides from Glycyrrhiza Uralensis Fisch
por: Chen, Jie, et al.
Publicado: (2017)

Inhibition Effect of Dictyophora Polysaccharides on Human Hepatocellular Carcinoma Cell Line HCC-LM3
por: Hu, Ting, et al.
Publicado: (2020)

Berberine Promotes Apoptosis of Colorectal Cancer via Regulation of the Long Non-Coding RNA (lncRNA) Cancer Susceptibility Candidate 2 (CASC2)/AU-Binding Factor 1 (AUF1)/B-Cell CLL/Lymphoma 2 (Bcl-2) Axis
por: Dai, Wei, et al.
Publicado: (2019)

The Effects of Ludartin on Cell Proliferation, Cell Migration, Cell Cycle Arrest and Apoptosis Are Associated with Upregulation of p21WAF1 in Saos-2 Osteosarcoma Cells In Vitro
por: Zhang, Shuang-li, et al.
Publicado: (2018)

Effects of Connexin43 Overexpression on U251 Cell Growth, Migration, and Apoptosis
por: Lu, Jia, et al.
Publicado: (2017)

Atorvastatin Enhances Effects of Radiotherapy on Prostate Cancer Cells and Xenograft Tumor Mice Through Triggering Interaction Between Bcl-2 and MSH2
por: He, Zhenhua, et al.
Publicado: (2020)

Cofilin-2 Acts as a Marker for Predicting Radiotherapy Response and Is a Potential Therapeutic Target in Nasopharyngeal Carcinoma
por: Yu, Bin-Bin, et al.
Publicado: (2018)

A Polysaccharide from Amusium Pleuronectes Combined with Praziquantel Treatment Ameliorates Hepatic Fibrosis in Schistosoma Japonicum-Infected Mice
por: Tang, Xiaoniu, et al.
Publicado: (2018)

Capilliposide C Sensitizes Esophageal Squamous Carcinoma Cells to Oxaliplatin by Inducing Apoptosis Through the PI3K/Akt/mTOR Pathway
por: Shen, Zhipeng, et al.
Publicado: (2017)

Inhibition of Proliferation of SGC7901 and BGC823 Human Gastric Cancer Cells by Ursolic Acid Occurs Through a Caspase-Dependent Apoptotic Pathway
por: Zhang, Jing, et al.
Publicado: (2019)

Upregulation of Nuclear Factor IA Suppresses Oxidized Low-Density Lipoprotein-Induced Endoplasmic Reticulum Stress and Apoptosis in Human Umbilical Vein Endothelial Cells
por: Zhou, Zhenyu, et al.
Publicado: (2019)

Long Noncoding RNA HOTTIP Promotes Nasopharyngeal Cancer Cell Proliferation, Migration, and Invasion by Inhibiting miR-4301
por: Shen, Meiqin, et al.
Publicado: (2019)

Taxol-Resistant Gene 1 (Txr1) Mediates Oxaliplatin Resistance by Inducing Autophagy in Human Nasopharyngeal Carcinoma Cells
por: Chi, Hua-ming, et al.
Publicado: (2019)

Induction of K562 Cell Apoptosis by As(4)S(4) via Down-Regulating miR181
por: Gong, Jiangjiang, et al.
Publicado: (2017)

Resveratrol Suppresses Human Nasopharyngeal Carcinoma Cell Growth Via Inhibiting Differentiation Antagonizing Non-Protein Coding RNA (DANCR) Expression
por: Zhang, Jiafeng, et al.
Publicado: (2020)

MicroRNA-7-5p Promotes Cisplatin Resistance of Cervical Cancer Cells and Modulation of Cellular Energy Homeostasis by Regulating the Expression of the PARP-1 and BCL2 Genes
por: Yang, Fengxia, et al.
Publicado: (2018)

SHOX CNE9/10 Knockout in U2OS Osteosarcoma Cells and Its Effects on Cell Growth and Apoptosis
por: Xu, Xue-Jiao, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_up6mcbh0d2d019kqdee39rmli6