EpEX/EpCAM and Oct4 or Klf4 alone are sufficient to generate induced pluripotent stem cells through STAT3 and HIF2α

Epithelial cell adhesion molecule (EpCAM) was reported to be cleaved into extracellular domain of EpCAM (EpEX) and intracellular domain of EpCAM (EpICD). We previously reported that EpCAM serves as a potent stem cell marker which is highly and selectively expressed by undifferentiated rather than di...

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Detalles Bibliográficos
Autores principales: Kuan, I.-I., Liang, Kang-Hao, Wang, Yi-Ping, Kuo, Ting-Wen, Meir, Yaa-Jyuhn James, Wu, Sareina Chiung-Yuan, Yang, Shang-Chih, Lu, Jean, Wu, Han-Chung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291097/
https://www.ncbi.nlm.nih.gov/pubmed/28157205
http://dx.doi.org/10.1038/srep41852

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291097/
https://www.ncbi.nlm.nih.gov/pubmed/28157205
http://dx.doi.org/10.1038/srep41852

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