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Efficient genome replication of hepatitis B virus using adenovirus vector: a compact pregenomic RNA-expression unit

The complicated replication mechanisms of hepatitis B virus (HBV) have impeded HBV studies and anti-HBV therapy development as well. Herein we report efficient genome replication of HBV applying adenovirus vectors (AdVs) showing high transduction efficiency. Even in primary hepatocytes derived from...

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Detalles Bibliográficos
Autores principales:	Suzuki, Mariko, Kondo, Saki, Yamasaki, Manabu, Matsuda, Norie, Nomoto, Akio, Suzuki, Tetsuro, Saito, Izumu, Kanegae, Yumi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291108/ https://www.ncbi.nlm.nih.gov/pubmed/28157182 http://dx.doi.org/10.1038/srep41851

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