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Longitudinal in vivo bioimaging of hepatocyte transcription factor activity following cholestatic liver injury in mice
Molecular mechanisms regulating liver repair following cholestatic injury remain largely unknown. We have combined a mouse model of acute cholestatic liver injury, partial bile duct ligation (pBDL), with a novel longitudinal bioimaging methodology to quantify transcription factor activity during hep...
Autores principales: | Delhove, Juliette M. K. M., Buckley, Suzanne M. K., Perocheau, Dany P., Karda, Rajvinder, Arbuthnot, Patrick, Henderson, Neil C., Waddington, Simon N., McKay, Tristan R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291111/ https://www.ncbi.nlm.nih.gov/pubmed/28157201 http://dx.doi.org/10.1038/srep41874 |
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