Cargando…

Prolonged excretion of type-2 poliovirus from a primary immune deficient patient during the transition to a type-2 poliovirus-free world, Israel, 2016

Wild poliovirus type-2 has been eradicated, use of live type-2 vaccine has been terminated globally, and all type-2 polioviruses are under strict laboratory containment protocols. Re-emergence may arise from prolonged asymptomatic excretion of poliovirus by hospitalised primary immune deficient (PID...

Descripción completa

Detalles Bibliográficos
Autores principales: Weil, Merav, Shulman, Lester M, Heiman, Sophia, Stauber, Tali, Alfandari, Jacqueline, Weiss, Leah, Silberstein, Ilana, Indenbaum, Viki, Mendelson, Ella, Sofer, Danit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291147/
https://www.ncbi.nlm.nih.gov/pubmed/27918258
http://dx.doi.org/10.2807/1560-7917.ES.2016.21.47.30408
Descripción
Sumario:Wild poliovirus type-2 has been eradicated, use of live type-2 vaccine has been terminated globally, and all type-2 polioviruses are under strict laboratory containment protocols. Re-emergence may arise from prolonged asymptomatic excretion of poliovirus by hospitalised primary immune deficient (PID) patients, as described here, through repeated exposure of close contacts to high titres of infected material. At this transition time, PID patients should be screened and hospital containment protocols updated in parallel with laboratory containment.