Cargando…

Hepatocyte growth factor secreted by bone marrow stem cell reduce ER stress and improves repair in alveolar epithelial II cells

Idiopathic Pulmonary Fibrosis (IPF) is a progressive, irreversible lung disease with complex pathophysiology. Evidence of endoplasmic reticulum (ER) stress has been reported in alveolar epithelial cells (AEC) in IPF patients. Secreted mediators from bone marrow stem cells (BMSC-cm) have regenerative...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nita, Izabela, Hostettler, Katrin, Tamo, Luca, Medová, Michaela, Bombaci, Giuseppe, Zhong, Jun, Allam, Ramanjaneyulu, Zimmer, Yitzhak, Roth, Michael, Geiser, Thomas, Gazdhar, Amiq
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291222/ https://www.ncbi.nlm.nih.gov/pubmed/28157203 http://dx.doi.org/10.1038/srep41901

Ejemplares similares

Culture of human alveolar epithelial type II cells by sprouting
por: Khan, Petra, et al.
Publicado: (2018)

HGF Expressing Stem Cells in Usual Interstitial Pneumonia Originate from the Bone Marrow and Are Antifibrotic
por: Gazdhar, Amiq, et al.
Publicado: (2013)

The secretome of induced pluripotent stem cells reduces lung fibrosis in part by hepatocyte growth factor
por: Gazdhar, Amiq, et al.
Publicado: (2014)

Multipotent mesenchymal stem cells in lung fibrosis
por: Hostettler, Katrin E., et al.
Publicado: (2017)

Interactome Analysis of iPSC Secretome and Its Effect on Macrophages In Vitro
por: Tamò, Luca, et al.
Publicado: (2021)

Enhancing CRISPR deletion via pharmacological delay of DNA-PKcs
por: Bosch-Guiteras, Núria, et al.
Publicado: (2021)

A new electrospray method for targeted gene delivery
por: Boehringer, Stephan, et al.
Publicado: (2018)

Anti-Fibrotic Effect of SDF-1β Overexpression in Bleomycin-Injured Rat Lung
por: Fytianos, Kleanthis, et al.
Publicado: (2022)

Transcriptomic profiling reveals disease-specific characteristics of epithelial cells in idiopathic pulmonary fibrosis
por: Boesch, Maximilian, et al.
Publicado: (2020)

The Molecular Crosstalk between the MET Receptor Tyrosine Kinase and the DNA Damage Response — Biological and Clinical Aspects
por: Medová, Michaela, et al.
Publicado: (2013)

Editorial: Exploiting DNA Damage Response in the Era of Precision Oncology
por: Zimmer, Yitzhak, et al.
Publicado: (2020)

A Comparative Analysis of Individual RAS Mutations in Cancer Biology
por: Muñoz-Maldonado, Carmen, et al.
Publicado: (2019)

Gene Network Analysis of Interstitial Macrophages After Treatment with Induced Pluripotent Stem Cells Secretome (iPSC-cm) in the Bleomycin Injured Rat Lung
por: Tamò, Luca, et al.
Publicado: (2017)

The relevance of tyrosine kinase inhibitors for global metabolic pathways in cancer
por: Poliaková, Michaela, et al.
Publicado: (2018)

CAR T cell-based immunotherapy and radiation therapy: potential, promises and risks
por: Hovhannisyan, Lusine, et al.
Publicado: (2023)

In Vivo Electroporation-Mediated, Intrahepatic Alpha1 Antitrypsin Gene Transfer Reduces Pulmonary Emphysema in Pallid Mice
por: Sutter, Marco A., et al.
Publicado: (2020)

Basal-Like Cell-Conditioned Medium Exerts Anti-Fibrotic Effects In Vitro and In Vivo
por: Khan, Petra, et al.
Publicado: (2022)

Nonviral Gene Delivery of Growth and Differentiation Factor 5 to Human Mesenchymal Stem Cells Injected into a 3D Bovine Intervertebral Disc Organ Culture System
por: Bucher, Christian, et al.
Publicado: (2013)

Time-dependent and somatically acquired mitochondrial DNA mutagenesis and respiratory chain dysfunction in a scleroderma model of lung fibrosis
por: Gazdhar, Amiq, et al.
Publicado: (2014)

Human Bronchial Epithelial Cells Induce CD141/CD123/DC-SIGN/FLT3 Monocytes That Promote Allogeneic Th17 Differentiation
por: Gazdhar, Amiq, et al.
Publicado: (2017)

Size-dependent accumulation of particles in lysosomes modulates dendritic cell function through impaired antigen degradation
por: Seydoux, Emilie, et al.
Publicado: (2014)

Prognostic and Predictive Biomarkers in Head and Neck Squamous Cell Carcinoma Treated with Radiotherapy—A Systematic Review
por: Schanne, Daniel H., et al.
Publicado: (2022)

Allies or enemies? The effect of regulatory T cells and related T lymphocytes on the profibrotic environment in bleomycin-injured lung mouse models
por: Seyran, Mutlu, et al.
Publicado: (2022)

Profiling Invasiveness in Head and Neck Cancer: Recent Contributions of Genomic and Transcriptomic Approaches
por: Nisa, Lluís, et al.
Publicado: (2015)

LRR-protein RNH1 dampens the inflammasome activation and is associated with COVID-19 severity
por: Bombaci, Giuseppe, et al.
Publicado: (2022)

PIK3CA hotspot mutations differentially impact responses to MET targeting in MET-driven and non-driven preclinical cancer models
por: Nisa, Lluís, et al.
Publicado: (2017)

Impact of MET targeting on tumor-associated angiogenesis and growth of MET mutations-driven models of liver cancer
por: Piguet, Anne-Christine, et al.
Publicado: (2015)

An oncogene addiction phosphorylation signature and its derived scores inform tumor responsiveness to targeted therapies
por: Orlando, Eleonora, et al.
Publicado: (2022)

Correction: An oncogene addiction phosphorylation signature and its derived scores inform tumor responsiveness to targeted therapies
por: Orlando, Eleonora, et al.
Publicado: (2023)

Deciphering MET‐dependent modulation of global cellular responses to DNA damage by quantitative phosphoproteomics
por: Bensimon, Ariel, et al.
Publicado: (2020)

Mitochondrial DNA mutations and respiratory chain dysfunction in idiopathic and connective tissue disease-related lung fibrosis
por: Jaeger, Veronika K., et al.
Publicado: (2019)

Efficacy of Combined in-vivo Electroporation-Mediated Gene Transfer of VEGF, HGF, and IL-10 on Skin Flap Survival, Monitored by Label-Free Optical Imaging: A Feasibility Study
por: Seyed Jafari, S. Morteza, et al.
Publicado: (2021)

Angiogenin (ANG)—Ribonuclease Inhibitor (RNH1) System in Protein Synthesis and Disease
por: Sarangdhar, Mayuresh Anant, et al.
Publicado: (2021)

Alveolar Basal Cells Differentiate towards Secretory Epithelial- and Aberrant Basaloid-like Cells In Vitro
por: Khan, Petra, et al.
Publicado: (2022)

A DNA-PK phosphorylation site on MET regulates its signaling interface with the DNA damage response
por: Koch, Jonas P., et al.
Publicado: (2023)

Inflammasome Activation in Myeloid Malignancies—Friend or Foe?
por: Andina, Nicola, et al.
Publicado: (2022)

Synergistic effect of the TLR5 agonist CBLB502 and its downstream effector IL-22 against liver injury
por: Melin, Nicolas, et al.
Publicado: (2021)

Human molecular genetics sheds light on the physiological significance of ribonuclease inhibitor (RNH1)
por: Sarangdhar, Mayuresh Anant, et al.
Publicado: (2023)

Electrospray Mediated Localized and Targeted Chemotherapy in a Mouse Model of Lung Cancer
por: Ruzgys, Paulius, et al.
Publicado: (2021)

Non-viral Gene Delivery Methods for Bone and Joints
por: Gantenbein, Benjamin, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_7aatqabgtom3d2239ppv3q9llu