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Identification and characterization of DNA sequences that prevent glucocorticoid receptor binding to nearby response elements

Out of the myriad of potential DNA binding sites of the glucocorticoid receptor (GR) found in the human genome, only a cell-type specific minority is actually bound, indicating that the presence of a recognition sequence alone is insufficient to specify where GR binds. Cooperative interactions with...

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Detalles Bibliográficos
Autores principales: Telorac, Jonas, Prykhozhij, Sergey V., Schöne, Stefanie, Meierhofer, David, Sauer, Sascha, Thomas-Chollier, Morgane, Meijsing, Sebastiaan H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291246/
https://www.ncbi.nlm.nih.gov/pubmed/27016732
http://dx.doi.org/10.1093/nar/gkw203