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Defining the multivalent functions of CTCF from chromatin state and three-dimensional chromatin interactions

CCCTC-binding factor (CTCF) is a multi-functional protein that is assigned various, even contradictory roles in the genome. High-throughput sequencing-based technologies such as ChIP-seq and Hi-C provided us the opportunity to assess the multivalent functions of CTCF in the human genome. The locatio...

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Detalles Bibliográficos
Autores principales: Lu, Yiming, Shan, Guangyu, Xue, Jiguo, Chen, Changsheng, Zhang, Chenggang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291250/
https://www.ncbi.nlm.nih.gov/pubmed/27067545
http://dx.doi.org/10.1093/nar/gkw249