Loss of the mitochondrial protein-only ribonuclease P complex causes aberrant tRNA processing and lethality in Drosophila

Proteins encoded by mitochondrial DNA are translated using mitochondrially encoded tRNAs and rRNAs. As with nuclear encoded tRNAs, mitochondrial tRNAs must be processed to become fully functional. The mitochondrial form of ribonuclease P (mt:RNase P) is responsible for 5′-end maturation and is compr...

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Detalles Bibliográficos
Autores principales: Sen, Aditya, Karasik, Agnes, Shanmuganathan, Aranganathan, Mirkovic, Elena, Koutmos, Markos, Cox, Rachel T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291253/
https://www.ncbi.nlm.nih.gov/pubmed/27131785
http://dx.doi.org/10.1093/nar/gkw338

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