Synergy between NMR measurements and MD simulations of protein/RNA complexes: application to the RRMs, the most common RNA recognition motifs

RNA recognition motif (RRM) proteins represent an abundant class of proteins playing key roles in RNA biology. We present a joint atomistic molecular dynamics (MD) and experimental study of two RRM-containing proteins bound with their single-stranded target RNAs, namely the Fox-1 and SRSF1 complexes...

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Detalles Bibliográficos
Autores principales: Krepl, Miroslav, Cléry, Antoine, Blatter, Markus, Allain, Frederic H.T., Sponer, Jiri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291263/
https://www.ncbi.nlm.nih.gov/pubmed/27193998
http://dx.doi.org/10.1093/nar/gkw438

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291263/
https://www.ncbi.nlm.nih.gov/pubmed/27193998
http://dx.doi.org/10.1093/nar/gkw438

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