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Synergy between NMR measurements and MD simulations of protein/RNA complexes: application to the RRMs, the most common RNA recognition motifs
RNA recognition motif (RRM) proteins represent an abundant class of proteins playing key roles in RNA biology. We present a joint atomistic molecular dynamics (MD) and experimental study of two RRM-containing proteins bound with their single-stranded target RNAs, namely the Fox-1 and SRSF1 complexes...
Autores principales: | Krepl, Miroslav, Cléry, Antoine, Blatter, Markus, Allain, Frederic H.T., Sponer, Jiri |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291263/ https://www.ncbi.nlm.nih.gov/pubmed/27193998 http://dx.doi.org/10.1093/nar/gkw438 |
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