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Quantitative modeling of gene expression using DNA shape features of binding sites
Prediction of gene expression levels driven by regulatory sequences is pivotal in genomic biology. A major focus in transcriptional regulation is sequence-to-expression modeling, which interprets the enhancer sequence based on transcription factor concentrations and DNA binding specificities and pre...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291265/ https://www.ncbi.nlm.nih.gov/pubmed/27257066 http://dx.doi.org/10.1093/nar/gkw446 |