How far from the SNP may the causative genes be?

While GWAS identify many disease-associated SNPs, using them to decipher disease mechanisms is hindered by the difficulty in mapping SNPs to genes. Most SNPs are in non-coding regions and it is often hard to identify the genes they implicate. To explore how far the SNP may be from the affected genes...

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Detalles Bibliográficos
Autores principales: Brodie, Aharon, Azaria, Johnathan Roy, Ofran, Yanay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291268/
https://www.ncbi.nlm.nih.gov/pubmed/27269582
http://dx.doi.org/10.1093/nar/gkw500

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291268/
https://www.ncbi.nlm.nih.gov/pubmed/27269582
http://dx.doi.org/10.1093/nar/gkw500

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