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How far from the SNP may the causative genes be?
While GWAS identify many disease-associated SNPs, using them to decipher disease mechanisms is hindered by the difficulty in mapping SNPs to genes. Most SNPs are in non-coding regions and it is often hard to identify the genes they implicate. To explore how far the SNP may be from the affected genes...
Autores principales: | Brodie, Aharon, Azaria, Johnathan Roy, Ofran, Yanay |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291268/ https://www.ncbi.nlm.nih.gov/pubmed/27269582 http://dx.doi.org/10.1093/nar/gkw500 |
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