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Probing the impact of chromatin conformation on genome editing tools
Transcription activator-like effector nucleases (TALENs) and RNA-guided nucleases derived from clustered, regularly interspaced, short palindromic repeats (CRISPR)-Cas9 systems have become ubiquitous genome editing tools. Despite this, the impact that distinct high-order chromatin conformations have...
Autores principales: | Chen, Xiaoyu, Rinsma, Marrit, Janssen, Josephine M., Liu, Jin, Maggio, Ignazio, Gonçalves, Manuel A.F.V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291272/ https://www.ncbi.nlm.nih.gov/pubmed/27280977 http://dx.doi.org/10.1093/nar/gkw524 |
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