Development of Cell‐Permeable, Non‐Helical Constrained Peptides to Target a Key Protein–Protein Interaction in Ovarian Cancer

There is a lack of current treatment options for ovarian clear cell carcinoma (CCC) and the cancer is often resistant to platinum‐based chemotherapy. Hence there is an urgent need for novel therapeutics. The transcription factor hepatocyte nuclear factor 1β (HNF1β) is ubiquitously overexpressed in C...

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Detalles Bibliográficos
Autores principales: Wiedmann, Mareike M., Tan, Yaw Sing, Wu, Yuteng, Aibara, Shintaro, Xu, Wenshu, Sore, Hannah F., Verma, Chandra S., Itzhaki, Laura, Stewart, Murray, Brenton, James D., Spring, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291322/
https://www.ncbi.nlm.nih.gov/pubmed/27918136
http://dx.doi.org/10.1002/anie.201609427

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291322/
https://www.ncbi.nlm.nih.gov/pubmed/27918136
http://dx.doi.org/10.1002/anie.201609427

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