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Inefficiencies and Patient Burdens in the Development of the Targeted Cancer Drug Sorafenib: A Systematic Review

Failure in cancer drug development exacts heavy burdens on patients and research systems. To investigate inefficiencies and burdens in targeted drug development in cancer, we conducted a systematic review of all prelicensure trials for the anticancer drug, sorafenib (Bayer/Onyx Pharmaceuticals). We...

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Detalles Bibliográficos
Autores principales:	Mattina, James, Carlisle, Benjamin, Hachem, Yasmina, Fergusson, Dean, Kimmelman, Jonathan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Meta-Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291369/ https://www.ncbi.nlm.nih.gov/pubmed/28158308 http://dx.doi.org/10.1371/journal.pbio.2000487

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