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Platelet full length TFPI-α in healthy volunteers is not affected by sex or hormonal use

BACKGROUND: Only 10% of plasma TFPIα (TFPI) exists in the full length form, the rest circulates as a C-terminally truncated form. However, blood platelets exclusively contain full length TFPI, which is released at the site of injury upon platelet activation, and which could play an important local r...

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Detalles Bibliográficos
Autores principales: Winckers, Kristien, Thomassen, Stella, ten Cate, Hugo, Hackeng, Tilman M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291377/
https://www.ncbi.nlm.nih.gov/pubmed/28158181
http://dx.doi.org/10.1371/journal.pone.0168273