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miR-375-3p negatively regulates osteogenesis by targeting and decreasing the expression levels of LRP5 and β-catenin

Wnt signaling pathways are essential for bone formation. Previous studies showed that Wnt signaling pathways were regulated by miR-375. Thus, we aim to explore whether miR-375 could affect osteogenesis. In the present study, we investigated the roles of miR-375 and its downstream targets. Firstly, w...

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Detalles Bibliográficos
Autores principales:	Sun, Tianhao, Li, Chen-Tian, Xiong, Lifeng, Ning, Ziyu, Leung, Frankie, Peng, Songlin, Lu, William W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291413/ https://www.ncbi.nlm.nih.gov/pubmed/28158288 http://dx.doi.org/10.1371/journal.pone.0171281

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