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Recursive random forest algorithm for constructing multilayered hierarchical gene regulatory networks that govern biological pathways
BACKGROUND: Present knowledge indicates a multilayered hierarchical gene regulatory network (ML-hGRN) often operates above a biological pathway. Although the ML-hGRN is very important for understanding how a pathway is regulated, there is almost no computational algorithm for directly constructing M...
Autores principales: | Deng, Wenping, Zhang, Kui, Busov, Victor, Wei, Hairong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291523/ https://www.ncbi.nlm.nih.gov/pubmed/28158291 http://dx.doi.org/10.1371/journal.pone.0171532 |
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