Impact of Single or Combined Genomic Alterations of TP53, MYC, and BCL2 on Survival of Patients With Diffuse Large B-Cell Lymphomas: A Retrospective Cohort Study

MYC and BCL2 translocations as well as TP53 deletion/mutation are known risk factors in diffuse large B-cell lymphoma (DLBCL) but their interplay is not well understood. In this retrospective cohort study, we evaluated the combined prognostic impact of TP53 deletion and mutation status, MYC and BCL2...

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Detalles Bibliográficos
Autores principales: Schiefer, Ana-Iris, Kornauth, Christoph, Simonitsch-Klupp, Ingrid, Skrabs, Cathrin, Masel, Eva Katharina, Streubel, Berthold, Vanura, Katrina, Walter, Karin, Migschitz, Brigitta, Stoiber, Dagmar, Sexl, Veronika, Raderer, Markus, Chott, Andreas, da Silva, Maria Gomes, Cabecadas, Jose, Müllauer, Leonhard, Jäger, Ulrich, Porpaczy, Edit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2015
Materias:
4800
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291628/
https://www.ncbi.nlm.nih.gov/pubmed/26717387
http://dx.doi.org/10.1097/MD.0000000000002388

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291628/
https://www.ncbi.nlm.nih.gov/pubmed/26717387
http://dx.doi.org/10.1097/MD.0000000000002388

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