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Impact of Single or Combined Genomic Alterations of TP53, MYC, and BCL2 on Survival of Patients With Diffuse Large B-Cell Lymphomas: A Retrospective Cohort Study
MYC and BCL2 translocations as well as TP53 deletion/mutation are known risk factors in diffuse large B-cell lymphoma (DLBCL) but their interplay is not well understood. In this retrospective cohort study, we evaluated the combined prognostic impact of TP53 deletion and mutation status, MYC and BCL2...
Autores principales: | Schiefer, Ana-Iris, Kornauth, Christoph, Simonitsch-Klupp, Ingrid, Skrabs, Cathrin, Masel, Eva Katharina, Streubel, Berthold, Vanura, Katrina, Walter, Karin, Migschitz, Brigitta, Stoiber, Dagmar, Sexl, Veronika, Raderer, Markus, Chott, Andreas, da Silva, Maria Gomes, Cabecadas, Jose, Müllauer, Leonhard, Jäger, Ulrich, Porpaczy, Edit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291628/ https://www.ncbi.nlm.nih.gov/pubmed/26717387 http://dx.doi.org/10.1097/MD.0000000000002388 |
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