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Center or periphery? Modeling the effects of focal adhesion placement during cell spreading
Focal adhesions are often observed at the cell’s periphery. We provide an explanation for this observation using a system-level mathematical model of a cell interacting with a two-dimensional substrate. The model describes the biological cell as a hypoelastic continuum material whose behavior is cou...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291721/ https://www.ncbi.nlm.nih.gov/pubmed/28158263 http://dx.doi.org/10.1371/journal.pone.0171430 |