Cargando…

MDM2 promoter polymorphism del1518 (rs3730485) and its impact on endometrial and ovarian cancer risk

BACKGROUND: The del1518 (rs3730485) polymorphism is an in/del variant in the MDM2 promoter P1. The variant is in complete linkage disequilibrium with MDM2 SNP309 (rs2279744) and has previously been found associated with an increased risk of colon cancer. In this study we assessed the impact of MDM2...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gansmo, Liv B., Bjørnslett, Merete, Halle, Mari Kyllesø, Salvesen, Helga B., Romundstad, Pål, Hveem, Kristian, Vatten, Lars, Dørum, Anne, Lønning, Per E., Knappskog, Stian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291962/ https://www.ncbi.nlm.nih.gov/pubmed/28158999 http://dx.doi.org/10.1186/s12885-017-3094-y

Ejemplares similares

Associations between the MDM2 promoter P1 polymorphism del1518 (rs3730485) and incidence of cancer of the breast, lung, colon and prostate
por: Gansmo, Liv B., et al.
Publicado: (2016)

The MDM4 SNP34091 (rs4245739) C-allele is associated with increased risk of ovarian—but not endometrial cancer
por: Gansmo, Liv B., et al.
Publicado: (2016)

MDM2 Promoter SNP344T>A (rs1196333) Status Does Not Affect Cancer Risk
por: Knappskog, Stian, et al.
Publicado: (2012)

Impact of the APOBEC3A/B deletion polymorphism on risk of ovarian cancer
por: Gansmo, Liv B., et al.
Publicado: (2021)

MDM4 SNP34091 (rs4245739) and its effect on breast‐, colon‐, lung‐, and prostate cancer risk
por: Gansmo, Liv B., et al.
Publicado: (2015)

MDM2 promoter SNP55 (rs2870820) affects risk of colon cancer but not breast-, lung-, or prostate cancer
por: Helwa, Reham, et al.
Publicado: (2016)

Effect of the MDM2 promoter polymorphisms SNP309T>G and SNP285G>C on the risk of ovarian cancer in BRCA1 mutation carriers
por: Bjørnslett, Merete, et al.
Publicado: (2012)

Prevalence of the CHEK2 R95* germline mutation
por: Knappskog, Stian, et al.
Publicado: (2016)

APOBEC3A/B deletion polymorphism and cancer risk
por: Gansmo, Liv B, et al.
Publicado: (2018)

APOBEC3A/B deletion polymorphism and endometrial cancer risk
por: Sofiyeva, Nigar, et al.
Publicado: (2022)

Impact of the MDM2 splice-variants MDM2-A, MDM2-B and MDM2-C on cytotoxic stress response in breast cancer cells
por: Huun, Johanna, et al.
Publicado: (2017)

The Functional Roles of the MDM2 Splice Variants P2-MDM2-10 and MDM2-∆5 in Breast Cancer Cells
por: Huun, Johanna, et al.
Publicado: (2017)

Population distribution and ancestry of the cancer protective MDM2 SNP285 (rs117039649)
por: Knappskog, Stian, et al.
Publicado: (2014)

MDM2 promoter SNP285 and SNP309; phylogeny and impact on cancer risk
por: Knappskog, Stian, et al.
Publicado: (2011)

Association Analysis of TP53 rs1042522, MDM2 rs2279744, rs3730485, MDM4 rs4245739 Variants and Acute Myeloid Leukemia Susceptibility, Risk Stratification Scores, and Clinical Features: An Exploratory Study
por: Tripon, Florin, et al.
Publicado: (2020)

MDM2 promoter del1518 polymorphism and cancer risk: evidence from 22,931 subjects
por: Hua, Wenfeng, et al.
Publicado: (2017)

C77G in PTPRC (CD45) is no risk allele for ovarian cancer, but associated with less aggressive disease
por: Landskron, Johannes, et al.
Publicado: (2017)

Chemosensitivity and p53; new tricks by an old dog
por: Lønning, Per E, et al.
Publicado: (2012)

BRCA1 methylation in newborns: genetic disposition, maternal transfer, environmental influence, or by chance only?
por: Lønning, Per Eystein, et al.
Publicado: (2018)

A case‐control study on the SNP309T → G and 40‐bp Del1518 of the MDM2 gene and a systematic review for MDM2 polymorphisms in the patients with breast cancer
por: Jalilvand, Amin, et al.
Publicado: (2020)

Effects of concomitant inactivation of p53 and pRb on response to doxorubicin treatment in breast cancer cell lines
por: Huun, Johanna, et al.
Publicado: (2017)

ramr: an R/Bioconductor package for detection of rare aberrantly methylated regions
por: Nikolaienko, Oleksii, et al.
Publicado: (2021)

epialleleR: an R/Bioconductor package for sensitive allele-specific methylation analysis in NGS data
por: Nikolaienko, Oleksii, et al.
Publicado: (2023)

Correction to Lancet Oncol 2021; 22: 1518–29
Publicado: (2022)

Influence of p53 Isoform Expression on Survival in High-Grade Serous Ovarian Cancers
por: Bischof, Katharina, et al.
Publicado: (2019)

TP53 status predicts long-term survival in locally advanced breast cancer after primary chemotherapy
por: Eikesdal, Hans P., et al.
Publicado: (2014)

Association between MDM2 rs2279744, MDM2 rs937283, and p21 rs1801270 polymorphisms and retinoblastoma susceptibility
por: Cao, Qixin, et al.
Publicado: (2018)

Predictive and Prognostic Impact of TP53 Mutations and MDM2 Promoter Genotype in Primary Breast Cancer Patients Treated with Epirubicin or Paclitaxel
por: Chrisanthar, Ranjan, et al.
Publicado: (2011)

Adjuvant treatment: the contribution of expression microarrays
por: Lønning, Per Eystein, et al.
Publicado: (2007)

Alterations of the retinoblastoma gene in metastatic breast cancer
por: Berge, Elisabet Ognedal, et al.
Publicado: (2011)

Constitutional Mosaic Epimutations - a hidden cause of cancer?
por: Lønning, Per E., et al.
Publicado: (2019)

Estrogens Correlate with PELP1 Expression in ER Positive Breast Cancer
por: Flågeng, Marianne Hauglid, et al.
Publicado: (2015)

The novel microRNAs hsa-miR-nov7 and hsa-miR-nov3 are over-expressed in locally advanced breast cancer
por: Poduval, Deepak, et al.
Publicado: (2020)

Correction: The novel microRNAs hsa-miR-nov7 and hsa-miR-nov3 are over-expressed in locally advanced breast cancer
por: Poduval, Deepak, et al.
Publicado: (2021)

Tres siglos de pensamiento económico, 1518-1817/Jesús Silva Herzog
por: Silva Herzog, Jesús, 1892-1985
Publicado: (1950)

Do parental heights influence pregnancy length?: a population-based prospective study, HUNT 2
por: Myklestad, Kirsti, et al.
Publicado: (2013)

Inverse Regulation of EGFR/HER1 and HER2-4 in Normal and Malignant Human Breast Tissue
por: Flågeng, Marianne Hauglid, et al.
Publicado: (2013)

Pacritinib (SB1518), a JAK2/FLT3 inhibitor for the treatment of acute myeloid leukemia
por: Hart, S, et al.
Publicado: (2011)

Elevated levels of the steroidogenic factor 1 are associated with over-expression of CYP19 in an oestrogen-producing testicular Leydig cell tumour
por: Straume, Anne Hege, et al.
Publicado: (2012)

High-Throughput Mutation Profiling of Primary and Metastatic Endometrial Cancers Identifies KRAS, FGFR2 and PIK3CA to Be Frequently Mutated
por: Krakstad, Camilla, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_6c3jjtrun0das6sn9n2t4920k0