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Super-Selective Mesenteric Embolization Provides Effective Control of Lower GI Bleeding

Introduction. We aimed to assess the efficacy and safety of digital subtraction angiography (DSA) and super-selective mesenteric artery embolization (SMAE) in managing lower GI bleeding (LGIB). Method. A retrospective case series of patients with LGIB treated with SMAE in our health service. Patient...

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Autores principales: Pham, Toan, Tran, Bob Anh, Ooi, Kevin, Mykytowycz, Marcus, McLaughlin, Stephen, Croxford, Matthew, Skinner, Iain, Faragher, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292126/
https://www.ncbi.nlm.nih.gov/pubmed/28210507
http://dx.doi.org/10.1155/2017/1074804
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author Pham, Toan
Tran, Bob Anh
Ooi, Kevin
Mykytowycz, Marcus
McLaughlin, Stephen
Croxford, Matthew
Skinner, Iain
Faragher, Ian
author_facet Pham, Toan
Tran, Bob Anh
Ooi, Kevin
Mykytowycz, Marcus
McLaughlin, Stephen
Croxford, Matthew
Skinner, Iain
Faragher, Ian
author_sort Pham, Toan
collection PubMed
description Introduction. We aimed to assess the efficacy and safety of digital subtraction angiography (DSA) and super-selective mesenteric artery embolization (SMAE) in managing lower GI bleeding (LGIB). Method. A retrospective case series of patients with LGIB treated with SMAE in our health service. Patients with confirmed active LGIB, on either radionuclide scintigraphy (RS) or contrast-enhanced multidetector CT angiography (CE-MDCT), were referred for DSA +/− SMAE. Data collected included patient characteristics, screening modality, bleeding territory, embolization technique, technical and clinical success, short-term to medium-term complications, 30-day mortality, and progression to surgery related to procedural failure or complications. Results. There were fifty-five hospital admissions with acute unstable lower gastrointestinal bleeding which were demonstrable on CE-MDCT or RS over a 31-month period. Eighteen patients proceed to embolization, with immediate success in all. Eight patients (44%) had clinical rebleeding after intervention, warranting repeated imaging. Only one case (5.6%) demonstrated radiological rebleeding and was reembolized. Complication rate was excellent: no bowel ischaemia, ischaemic stricture, progression to surgery, or 30-day mortality. Conclusion. SMAE is a viable, safe, and effective first-line management for localised LGIB. Our results overall compare favourably with the published experiences of other institutions. It is now accepted practice at our institution to manage localised LGIB with embolization.
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spelling pubmed-52921262017-02-16 Super-Selective Mesenteric Embolization Provides Effective Control of Lower GI Bleeding Pham, Toan Tran, Bob Anh Ooi, Kevin Mykytowycz, Marcus McLaughlin, Stephen Croxford, Matthew Skinner, Iain Faragher, Ian Radiol Res Pract Research Article Introduction. We aimed to assess the efficacy and safety of digital subtraction angiography (DSA) and super-selective mesenteric artery embolization (SMAE) in managing lower GI bleeding (LGIB). Method. A retrospective case series of patients with LGIB treated with SMAE in our health service. Patients with confirmed active LGIB, on either radionuclide scintigraphy (RS) or contrast-enhanced multidetector CT angiography (CE-MDCT), were referred for DSA +/− SMAE. Data collected included patient characteristics, screening modality, bleeding territory, embolization technique, technical and clinical success, short-term to medium-term complications, 30-day mortality, and progression to surgery related to procedural failure or complications. Results. There were fifty-five hospital admissions with acute unstable lower gastrointestinal bleeding which were demonstrable on CE-MDCT or RS over a 31-month period. Eighteen patients proceed to embolization, with immediate success in all. Eight patients (44%) had clinical rebleeding after intervention, warranting repeated imaging. Only one case (5.6%) demonstrated radiological rebleeding and was reembolized. Complication rate was excellent: no bowel ischaemia, ischaemic stricture, progression to surgery, or 30-day mortality. Conclusion. SMAE is a viable, safe, and effective first-line management for localised LGIB. Our results overall compare favourably with the published experiences of other institutions. It is now accepted practice at our institution to manage localised LGIB with embolization. Hindawi Publishing Corporation 2017 2017-01-22 /pmc/articles/PMC5292126/ /pubmed/28210507 http://dx.doi.org/10.1155/2017/1074804 Text en Copyright © 2017 Toan Pham et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Pham, Toan
Tran, Bob Anh
Ooi, Kevin
Mykytowycz, Marcus
McLaughlin, Stephen
Croxford, Matthew
Skinner, Iain
Faragher, Ian
Super-Selective Mesenteric Embolization Provides Effective Control of Lower GI Bleeding
title Super-Selective Mesenteric Embolization Provides Effective Control of Lower GI Bleeding
title_full Super-Selective Mesenteric Embolization Provides Effective Control of Lower GI Bleeding
title_fullStr Super-Selective Mesenteric Embolization Provides Effective Control of Lower GI Bleeding
title_full_unstemmed Super-Selective Mesenteric Embolization Provides Effective Control of Lower GI Bleeding
title_short Super-Selective Mesenteric Embolization Provides Effective Control of Lower GI Bleeding
title_sort super-selective mesenteric embolization provides effective control of lower gi bleeding
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292126/
https://www.ncbi.nlm.nih.gov/pubmed/28210507
http://dx.doi.org/10.1155/2017/1074804
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