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Adaptations in Basal and Hypothalamic–Pituitary–Adrenal-Activated Deoxycorticosterone Responses Following Ethanol Self-administration in Cynomolgus Monkeys

Acute ethanol activates the hypothalamic–pituitary–adrenal (HPA) axis, while long-term exposure results in a blunted neuroendocrine state, particularly with regards to the primary endpoint, cortisol, the primary glucocorticoid produced in the adrenal cortex. However, it is unknown if this dampened n...

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Detalles Bibliográficos
Autores principales: Jimenez, Vanessa A., Porcu, Patrizia, Morrow, A. Leslie, Grant, Kathleen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292619/
https://www.ncbi.nlm.nih.gov/pubmed/28220108
http://dx.doi.org/10.3389/fendo.2017.00019