Gemcitabine induced cardiomyopathy: a case of multiple hit cardiotoxicity

Gemcitabine is a commonly used antineoplastic agent used to treat a variety of cancers with rarely reported cardiac side effects. We describe a case of a 67‐year‐old woman with follicular lymphoma who experienced a rarely reported side effect of gemcitabine: cardiomyopathy. This case highlights a mu...

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Detalles Bibliográficos
Autores principales: Mohebali, Donya, Matos, Jason, Chang, James Ducksoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292629/
https://www.ncbi.nlm.nih.gov/pubmed/28217315
http://dx.doi.org/10.1002/ehf2.12113
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author Mohebali, Donya
Matos, Jason
Chang, James Ducksoon
author_facet Mohebali, Donya
Matos, Jason
Chang, James Ducksoon
author_sort Mohebali, Donya
collection PubMed
description Gemcitabine is a commonly used antineoplastic agent used to treat a variety of cancers with rarely reported cardiac side effects. We describe a case of a 67‐year‐old woman with follicular lymphoma who experienced a rarely reported side effect of gemcitabine: cardiomyopathy. This case highlights a multiple hit mechanism of myocyte damage that may occur following the use of multiple cardio‐toxic agents despite their administration in doses not associated with cardiotoxicity.
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spelling pubmed-52926292017-02-17 Gemcitabine induced cardiomyopathy: a case of multiple hit cardiotoxicity Mohebali, Donya Matos, Jason Chang, James Ducksoon ESC Heart Fail Case Reports Gemcitabine is a commonly used antineoplastic agent used to treat a variety of cancers with rarely reported cardiac side effects. We describe a case of a 67‐year‐old woman with follicular lymphoma who experienced a rarely reported side effect of gemcitabine: cardiomyopathy. This case highlights a multiple hit mechanism of myocyte damage that may occur following the use of multiple cardio‐toxic agents despite their administration in doses not associated with cardiotoxicity. John Wiley and Sons Inc. 2016-09-21 /pmc/articles/PMC5292629/ /pubmed/28217315 http://dx.doi.org/10.1002/ehf2.12113 Text en © 2016 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on behalf of the European Society of Cardiology. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs (http://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Reports
Mohebali, Donya
Matos, Jason
Chang, James Ducksoon
Gemcitabine induced cardiomyopathy: a case of multiple hit cardiotoxicity
title Gemcitabine induced cardiomyopathy: a case of multiple hit cardiotoxicity
title_full Gemcitabine induced cardiomyopathy: a case of multiple hit cardiotoxicity
title_fullStr Gemcitabine induced cardiomyopathy: a case of multiple hit cardiotoxicity
title_full_unstemmed Gemcitabine induced cardiomyopathy: a case of multiple hit cardiotoxicity
title_short Gemcitabine induced cardiomyopathy: a case of multiple hit cardiotoxicity
title_sort gemcitabine induced cardiomyopathy: a case of multiple hit cardiotoxicity
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292629/
https://www.ncbi.nlm.nih.gov/pubmed/28217315
http://dx.doi.org/10.1002/ehf2.12113
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AT matosjason gemcitabineinducedcardiomyopathyacaseofmultiplehitcardiotoxicity
AT changjamesducksoon gemcitabineinducedcardiomyopathyacaseofmultiplehitcardiotoxicity

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