NF-κB Links TLR2 and PAR1 to Soluble Immunomodulator Factor Secretion in Human Platelets

The primary toll-like receptor (TLR)-mediated immune cell response pathway common for all TLRs is MyD88-dependent activation of NF-κB, a seminal transcription factor for many chemokines and cytokines. Remarkably, anucleate platelets express the NF-κB machinery, whose role in platelets remains poorly...

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Detalles Bibliográficos
Autores principales: Damien, Pauline, Cognasse, Fabrice, Payrastre, Bernard, Spinelli, Sherry L., Blumberg, Neil, Arthaud, Charles-Antoine, Eyraud, Marie-Ange, Phipps, Richard P., McNicol, Archibald, Pozzetto, Bruno, Garraud, Olivier, Hamzeh-Cognasse, Hind
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292648/
https://www.ncbi.nlm.nih.gov/pubmed/28220122
http://dx.doi.org/10.3389/fimmu.2017.00085

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