Fanconi anemia protein FANCD2 is activated by AICAR, a modulator of AMPK and cellular energy metabolism

FANCD2 is a pivotal molecule in the pathogenesis of Fanconi anemia (FA), an autosomal recessive human syndrome with diverse clinical phenotypes, including cancer predisposition, short stature, and hematological abnormalities. In our previous study, we detected the functional association of FANC prot...

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Detalles Bibliográficos
Autores principales: Chun, Min Jeong, Choi, Hana, Jun, Dong Wha, Kim, Sunshin, Kim, Yong‐Nyun, Kim, Soo‐Youl, Lee, Chang‐Hun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292659/
https://www.ncbi.nlm.nih.gov/pubmed/28174693
http://dx.doi.org/10.1002/2211-5463.12185

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