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The gene expression of numerous SLC transporters is altered in the immortalized hypothalamic cell line N25/2 following amino acid starvation

Amino acids are known to play a key role in gene expression regulation, and in mammalian cells, amino acid signaling is mainly mediated via two pathways, the mammalian target of rapamycin complex 1 (mTORC1) pathway and the amino acid responsive (AAR) pathway. It is vital for cells to have a system t...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Hellsten, Sofie V., Lekholm, Emilia, Ahmad, Tauseef, Fredriksson, Robert
التنسيق: Online مقال نص
اللغة:English
منشور في: John Wiley and Sons Inc. 2017
الموضوعات:
الوصول للمادة أونلاين:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292668/
https://www.ncbi.nlm.nih.gov/pubmed/28174690
http://dx.doi.org/10.1002/2211-5463.12181