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Human embryonic and induced pluripotent stem cells maintain phenotype but alter their metabolism after exposure to ROCK inhibitor

Human pluripotent stem cells (hPSCs) are adhesion-dependent cells that require cultivation in colonies to maintain growth and pluripotency. Robust differentiation protocols necessitate single cell cultures that are achieved by use of ROCK (Rho kinase) inhibitors. ROCK inhibition enables maintenance...

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Detalles Bibliográficos
Autores principales:	Vernardis, Spyros I., Terzoudis, Konstantinos, Panoskaltsis, Nicki, Mantalaris, Athanasios
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292706/ https://www.ncbi.nlm.nih.gov/pubmed/28165055 http://dx.doi.org/10.1038/srep42138

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