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Novel Treatment of Chronic Graft-Versus-Host Disease in Mice Using the ER Stress Reducer 4-Phenylbutyric Acid
Chronic graft-versus-host disease (cGVHD) is a notorious complication of allogeneic hematopoietic stem cell transplantation and causes disabling systemic inflammation and fibrosis. In this novel study, we focused on a relationship between endoplasmic reticulum (ER) stress and cGVHD, and aimed to cre...
Autores principales: | Mukai, Shin, Ogawa, Yoko, Urano, Fumihiko, Kudo-Saito, Chie, Kawakami, Yutaka, Tsubota, Kazuo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292729/ https://www.ncbi.nlm.nih.gov/pubmed/28165054 http://dx.doi.org/10.1038/srep41939 |
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