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MicroRNA-130b targets PTEN to mediate drug resistance and proliferation of breast cancer cells via the PI3K/Akt signaling pathway

Multidrug resistance (MDR) correlates with treatment failure and poor prognosis among breast cancer patients. This study was aimed to investigate the possible mechanism by which microRNA-130b-3p (miR-130b) mediates the chemoresistance and proliferation of breast cancer. MiR-130b was found to be up-r...

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Detalles Bibliográficos
Autores principales: Miao, Yuan, Zheng, Wei, Li, Nana, Su, Zhen, Zhao, Lifen, Zhou, Huimin, Jia, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292739/
https://www.ncbi.nlm.nih.gov/pubmed/28165066
http://dx.doi.org/10.1038/srep41942