Intracellular pH-responsive and rituximab-conjugated mesoporous silica nanoparticles for targeted drug delivery to lymphoma B cells

BACKGROUND: One of the main problems in B cell lymphoma treatment is severe adverse effects and low therapeutic efficacy resulting from systemic chemotherapy. A pH-sensitive controlled drug release system based on mesoporous silica nanoparticles was constructed for targeted drug delivery to tumor ce...

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Detalles Bibliográficos
Autores principales: Zhou, Shoubing, Wu, Dan, Yin, Xiaodong, Jin, Xiaoxiao, Zhang, Xiu, Zheng, Shiya, Wang, Cailian, Liu, Yanwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292796/
https://www.ncbi.nlm.nih.gov/pubmed/28166836
http://dx.doi.org/10.1186/s13046-017-0492-6

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