Influence of gold nanoparticle surface chemistry and diameter upon Alzheimer’s disease amyloid-β protein aggregation

BACKGROUND: Deposits of aggregated amyloid-β protein (Aβ) are a pathological hallmark of Alzheimer’s disease (AD). Thus, one therapeutic strategy is to eliminate these deposits by halting Aβ aggregation. While a variety of possible aggregation inhibitors have been explored, only nanoparticles (NPs)...

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Detalles Bibliográficos
Autores principales: Moore, Kelly A., Pate, Kayla M., Soto-Ortega, Deborah D., Lohse, Samuel, van der Munnik, Nicholas, Lim, Mihyun, Jackson, Kaliah S., Lyles, Venetia D., Jones, Lemeisha, Glassgow, Nisha, Napumecheno, Vanessa M., Mobley, Shanee, Uline, Mark J., Mahtab, Rahina, Murphy, Catherine J., Moss, Melissa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292815/
https://www.ncbi.nlm.nih.gov/pubmed/28191036
http://dx.doi.org/10.1186/s13036-017-0047-6

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