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Intercomparison in Cytogenetic Dosimetry among 22 Laboratories in China

As part of a regional International Atomic Energy Agency-coordinated research project with the support from the National Health and Family Planning Commission of China, 22 laboratories participated in the intercomparison in cytogenetic dosimetry in China. Slides for chromosomal aberrations were prep...

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Autores principales: Liu, Jian Xiang, Pan, Yan, Ruan, Jian Lei, Piao, Chunnan, Su, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292918/
https://www.ncbi.nlm.nih.gov/pubmed/28217282
http://dx.doi.org/10.4103/2041-9414.197164
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author Liu, Jian Xiang
Pan, Yan
Ruan, Jian Lei
Piao, Chunnan
Su, Xu
author_facet Liu, Jian Xiang
Pan, Yan
Ruan, Jian Lei
Piao, Chunnan
Su, Xu
author_sort Liu, Jian Xiang
collection PubMed
description As part of a regional International Atomic Energy Agency-coordinated research project with the support from the National Health and Family Planning Commission of China, 22 laboratories participated in the intercomparison in cytogenetic dosimetry in China. Slides for chromosomal aberrations were prepared by the Department of Radiation Epidemiology, National Institute for Radiological Protection, which organized the exercise. Slides were sent to the other participating laboratories through Express Mail Service. For estimates of dose, each laboratory scored the frequency of dicentrics plus centric rings chromosomes. The whole blood samples were irradiated with (60)Co γ-rays (1.3 Gy, 2.4 Gy and 1.5 Gy, 2.6 Gy). Each laboratory got one group of the slides. Ten of the 44 estimates of dose fell within ±5% of the true physical dose, 12 fell within ±5–10%, 9 fell within ±10–15%, 12 fell within ±15–20%, while only one sample fell ± >20%. The evaluation of the respective dose was achieved by 21 laboratories.
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spelling pubmed-52929182017-02-17 Intercomparison in Cytogenetic Dosimetry among 22 Laboratories in China Liu, Jian Xiang Pan, Yan Ruan, Jian Lei Piao, Chunnan Su, Xu Genome Integr Original Article As part of a regional International Atomic Energy Agency-coordinated research project with the support from the National Health and Family Planning Commission of China, 22 laboratories participated in the intercomparison in cytogenetic dosimetry in China. Slides for chromosomal aberrations were prepared by the Department of Radiation Epidemiology, National Institute for Radiological Protection, which organized the exercise. Slides were sent to the other participating laboratories through Express Mail Service. For estimates of dose, each laboratory scored the frequency of dicentrics plus centric rings chromosomes. The whole blood samples were irradiated with (60)Co γ-rays (1.3 Gy, 2.4 Gy and 1.5 Gy, 2.6 Gy). Each laboratory got one group of the slides. Ten of the 44 estimates of dose fell within ±5% of the true physical dose, 12 fell within ±5–10%, 9 fell within ±10–15%, 12 fell within ±15–20%, while only one sample fell ± >20%. The evaluation of the respective dose was achieved by 21 laboratories. Medknow Publications & Media Pvt Ltd 2016-12-30 /pmc/articles/PMC5292918/ /pubmed/28217282 http://dx.doi.org/10.4103/2041-9414.197164 Text en Copyright: © 2016 Genome Integrity http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Original Article
Liu, Jian Xiang
Pan, Yan
Ruan, Jian Lei
Piao, Chunnan
Su, Xu
Intercomparison in Cytogenetic Dosimetry among 22 Laboratories in China
title Intercomparison in Cytogenetic Dosimetry among 22 Laboratories in China
title_full Intercomparison in Cytogenetic Dosimetry among 22 Laboratories in China
title_fullStr Intercomparison in Cytogenetic Dosimetry among 22 Laboratories in China
title_full_unstemmed Intercomparison in Cytogenetic Dosimetry among 22 Laboratories in China
title_short Intercomparison in Cytogenetic Dosimetry among 22 Laboratories in China
title_sort intercomparison in cytogenetic dosimetry among 22 laboratories in china
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292918/
https://www.ncbi.nlm.nih.gov/pubmed/28217282
http://dx.doi.org/10.4103/2041-9414.197164
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