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Restenosis Inhibition and Re-differentiation of TGFβ/Smad3-activated Smooth Muscle Cells by Resveratrol
To date, there is no periadventitial drug delivery method available in the clinic to prevent restenotic failure of open vascular reconstructions. Resveratrol is a promising anti-restenotic natural drug but subject to low bioavailability when systemically administered. In order to reconcile these two...
Autores principales: | Zhu, Yichen, Takayama, Toshio, Wang, Bowen, Kent, Alycia, Zhang, Mengxue, Binder, Bernard Y.K., Urabe, Go, Shi, Yatao, DiRenzo, Daniel, Goel, Shakti A., Zhou, Yifan, Little, Christopher, Roenneburg, Drew A., Shi, Xu Dong, Li, Lingjun, Murphy, William L., Kent, K. Craig, Ke, Jianjuan, Guo, Lian-Wang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292946/ https://www.ncbi.nlm.nih.gov/pubmed/28165488 http://dx.doi.org/10.1038/srep41916 |
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