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Apical dendrite degeneration, a novel cellular pathology for Betz cells in ALS

Apical dendrites of Betz cells are important sites for the integration of cortical input, however their health has not been fully assessed in ALS patients. We investigated the primary motor cortices isolated from post-mortem normal control subjects, patients with familial ALS (fALS), sporadic ALS (s...

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Detalles Bibliográficos
Autores principales: Genç, Barış, Jara, Javier H., Lagrimas, Amiko K. B., Pytel, Peter, Roos, Raymond P., Mesulam, M. Marsel, Geula, Changiz, Bigio, Eileen H., Özdinler, P. Hande
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292972/
https://www.ncbi.nlm.nih.gov/pubmed/28165465
http://dx.doi.org/10.1038/srep41765