Measurement of immunofunctional leptin to detect and monitor patients with functional leptin deficiency

CONTEXT AND AIMS: Functional leptin deficiency is characterized by high levels of circulating immunoreactive leptin (irLep), but a reduced bioactivity of the hormone due to defective receptor binding. As a result of the fact that affected patients can be successfully treated with metreleptin, it was...

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Detalles Bibliográficos
Autores principales: Wabitsch, Martin, Pridzun, Lutz, Ranke, Michael, von Schnurbein, Julia, Moss, Anja, Brandt, Stephanie, Kohlsdorf, Katja, Moepps, Barbara, Schaab, Michael, Funcke, Jan-Bernd, Gierschik, Peter, Fischer-Posovszky, Pamela, Flehmig, Bertram, Kratzsch, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2016
Materias:
Clinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292973/
https://www.ncbi.nlm.nih.gov/pubmed/28007844
http://dx.doi.org/10.1530/EJE-16-0821

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