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Early commitment and robust differentiation in colonic crypts
Tissue stem cells produce a constant flux of differentiated cells with distinct proportions. Here, we show that stem cells in colonic crypts differentiate early to form precisely 1:3 ratio of secretory to absorptive cells. This precision is surprising, as there are only eight stem cells making irrev...
Autores principales: | Tóth, Beáta, Ben‐Moshe, Shani, Gavish, Avishai, Barkai, Naama, Itzkovitz, Shalev |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293156/ https://www.ncbi.nlm.nih.gov/pubmed/28049136 http://dx.doi.org/10.15252/msb.20167283 |
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