Bacterial internalization is required to trigger NIK-dependent NF-κB activation in response to the bacterial type three secretion system

Infection of human cells with Yersinia pseudotuberculosis expressing a functional type III secretion system (T3SS) leads to activation of host NF-κB. We show that the Yersinia T3SS activates distinct NF-κB pathways dependent upon bacterial subcellular localization. We found that wildtype Yersinia ab...

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Detalles Bibliográficos
Autores principales: Duncan, Miles C., Herrera, Natalia G., Johnson, Kevin S., Engel, Joanne N., Auerbuch, Victoria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293232/
https://www.ncbi.nlm.nih.gov/pubmed/28166267
http://dx.doi.org/10.1371/journal.pone.0171406

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