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Gene Expression Noise Enhances Robust Organization of the Early Mammalian Blastocyst
A critical event in mammalian embryo development is construction of an inner cell mass surrounded by a trophoectoderm (a shell of cells that later form extraembryonic structures). We utilize multi-scale, stochastic modeling to investigate the design principles responsible for robust establishment of...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293272/ https://www.ncbi.nlm.nih.gov/pubmed/28114387 http://dx.doi.org/10.1371/journal.pcbi.1005320 |