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Sexual dimorphism in the osmopressor response following water ingestion
There is conflicting evidence as to whether water drinking elicits a pressor response in healthy young adults. The inclusion of a variable number of women may have contributed to the discrepancies found in past research. Thus, we aimed at exploring whether the osmopressor response follows a sexually...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293556/ https://www.ncbi.nlm.nih.gov/pubmed/27129286 http://dx.doi.org/10.1042/BSR20150276 |
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author | Mendonca, Goncalo V. Teodósio, Carolina Lucena, Rui Pereira, Fernando D. |
author_facet | Mendonca, Goncalo V. Teodósio, Carolina Lucena, Rui Pereira, Fernando D. |
author_sort | Mendonca, Goncalo V. |
collection | PubMed |
description | There is conflicting evidence as to whether water drinking elicits a pressor response in healthy young adults. The inclusion of a variable number of women may have contributed to the discrepancies found in past research. Thus, we aimed at exploring whether the osmopressor response follows a sexually dimorphic pattern. In a randomized fashion, 31 healthy adults (16 men; 15 women, aged 18–40 years) ingested 50 and 500 ml of water before completing a resting protocol on two separate days. Arterial blood pressure, heart rate and spectral heart rate variability were measured in the seated position at pre- and post-25 min of water ingestion. Women responded to 500 ml of water with a greater proportion of change in diastolic and mean arterial pressure (MAP) (P<0.05). Conversely, the percent change in systolic blood pressure (SBP) and heart rate was not different between sexes after 500 ml of water. Overall, women demonstrated lower blood pressure, but higher resting heart rate compared with men (P<0.05). In contrast, heart rate variability was similar between sexes before and after ingesting either volume of water. There was a bradycardic effect of water and, irrespectively of sex; this was accompanied by increased high frequency power (HF) (P<0.05). We conclude that women display a greater magnitude of pressor response than men post-water ingestion. Accordingly, we provide direct evidence of sexual dimorphism in the haemodynamic response to water intake in young healthy adults. |
format | Online Article Text |
id | pubmed-5293556 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Portland Press Ltd. |
record_format | MEDLINE/PubMed |
spelling | pubmed-52935562017-02-14 Sexual dimorphism in the osmopressor response following water ingestion Mendonca, Goncalo V. Teodósio, Carolina Lucena, Rui Pereira, Fernando D. Biosci Rep Original Papers There is conflicting evidence as to whether water drinking elicits a pressor response in healthy young adults. The inclusion of a variable number of women may have contributed to the discrepancies found in past research. Thus, we aimed at exploring whether the osmopressor response follows a sexually dimorphic pattern. In a randomized fashion, 31 healthy adults (16 men; 15 women, aged 18–40 years) ingested 50 and 500 ml of water before completing a resting protocol on two separate days. Arterial blood pressure, heart rate and spectral heart rate variability were measured in the seated position at pre- and post-25 min of water ingestion. Women responded to 500 ml of water with a greater proportion of change in diastolic and mean arterial pressure (MAP) (P<0.05). Conversely, the percent change in systolic blood pressure (SBP) and heart rate was not different between sexes after 500 ml of water. Overall, women demonstrated lower blood pressure, but higher resting heart rate compared with men (P<0.05). In contrast, heart rate variability was similar between sexes before and after ingesting either volume of water. There was a bradycardic effect of water and, irrespectively of sex; this was accompanied by increased high frequency power (HF) (P<0.05). We conclude that women display a greater magnitude of pressor response than men post-water ingestion. Accordingly, we provide direct evidence of sexual dimorphism in the haemodynamic response to water intake in young healthy adults. Portland Press Ltd. 2016-06-17 /pmc/articles/PMC5293556/ /pubmed/27129286 http://dx.doi.org/10.1042/BSR20150276 Text en © 2016 The Author(s) http://creativecommons.org/licenses/by/4.0/ This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution Licence 4.0 (CC BY) (http://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Original Papers Mendonca, Goncalo V. Teodósio, Carolina Lucena, Rui Pereira, Fernando D. Sexual dimorphism in the osmopressor response following water ingestion |
title | Sexual dimorphism in the osmopressor response following water ingestion |
title_full | Sexual dimorphism in the osmopressor response following water ingestion |
title_fullStr | Sexual dimorphism in the osmopressor response following water ingestion |
title_full_unstemmed | Sexual dimorphism in the osmopressor response following water ingestion |
title_short | Sexual dimorphism in the osmopressor response following water ingestion |
title_sort | sexual dimorphism in the osmopressor response following water ingestion |
topic | Original Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293556/ https://www.ncbi.nlm.nih.gov/pubmed/27129286 http://dx.doi.org/10.1042/BSR20150276 |
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