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Sexual dimorphism in the osmopressor response following water ingestion

There is conflicting evidence as to whether water drinking elicits a pressor response in healthy young adults. The inclusion of a variable number of women may have contributed to the discrepancies found in past research. Thus, we aimed at exploring whether the osmopressor response follows a sexually...

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Autores principales: Mendonca, Goncalo V., Teodósio, Carolina, Lucena, Rui, Pereira, Fernando D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293556/
https://www.ncbi.nlm.nih.gov/pubmed/27129286
http://dx.doi.org/10.1042/BSR20150276
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author Mendonca, Goncalo V.
Teodósio, Carolina
Lucena, Rui
Pereira, Fernando D.
author_facet Mendonca, Goncalo V.
Teodósio, Carolina
Lucena, Rui
Pereira, Fernando D.
author_sort Mendonca, Goncalo V.
collection PubMed
description There is conflicting evidence as to whether water drinking elicits a pressor response in healthy young adults. The inclusion of a variable number of women may have contributed to the discrepancies found in past research. Thus, we aimed at exploring whether the osmopressor response follows a sexually dimorphic pattern. In a randomized fashion, 31 healthy adults (16 men; 15 women, aged 18–40 years) ingested 50 and 500 ml of water before completing a resting protocol on two separate days. Arterial blood pressure, heart rate and spectral heart rate variability were measured in the seated position at pre- and post-25 min of water ingestion. Women responded to 500 ml of water with a greater proportion of change in diastolic and mean arterial pressure (MAP) (P<0.05). Conversely, the percent change in systolic blood pressure (SBP) and heart rate was not different between sexes after 500 ml of water. Overall, women demonstrated lower blood pressure, but higher resting heart rate compared with men (P<0.05). In contrast, heart rate variability was similar between sexes before and after ingesting either volume of water. There was a bradycardic effect of water and, irrespectively of sex; this was accompanied by increased high frequency power (HF) (P<0.05). We conclude that women display a greater magnitude of pressor response than men post-water ingestion. Accordingly, we provide direct evidence of sexual dimorphism in the haemodynamic response to water intake in young healthy adults.
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spelling pubmed-52935562017-02-14 Sexual dimorphism in the osmopressor response following water ingestion Mendonca, Goncalo V. Teodósio, Carolina Lucena, Rui Pereira, Fernando D. Biosci Rep Original Papers There is conflicting evidence as to whether water drinking elicits a pressor response in healthy young adults. The inclusion of a variable number of women may have contributed to the discrepancies found in past research. Thus, we aimed at exploring whether the osmopressor response follows a sexually dimorphic pattern. In a randomized fashion, 31 healthy adults (16 men; 15 women, aged 18–40 years) ingested 50 and 500 ml of water before completing a resting protocol on two separate days. Arterial blood pressure, heart rate and spectral heart rate variability were measured in the seated position at pre- and post-25 min of water ingestion. Women responded to 500 ml of water with a greater proportion of change in diastolic and mean arterial pressure (MAP) (P<0.05). Conversely, the percent change in systolic blood pressure (SBP) and heart rate was not different between sexes after 500 ml of water. Overall, women demonstrated lower blood pressure, but higher resting heart rate compared with men (P<0.05). In contrast, heart rate variability was similar between sexes before and after ingesting either volume of water. There was a bradycardic effect of water and, irrespectively of sex; this was accompanied by increased high frequency power (HF) (P<0.05). We conclude that women display a greater magnitude of pressor response than men post-water ingestion. Accordingly, we provide direct evidence of sexual dimorphism in the haemodynamic response to water intake in young healthy adults. Portland Press Ltd. 2016-06-17 /pmc/articles/PMC5293556/ /pubmed/27129286 http://dx.doi.org/10.1042/BSR20150276 Text en © 2016 The Author(s) http://creativecommons.org/licenses/by/4.0/ This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution Licence 4.0 (CC BY) (http://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Papers
Mendonca, Goncalo V.
Teodósio, Carolina
Lucena, Rui
Pereira, Fernando D.
Sexual dimorphism in the osmopressor response following water ingestion
title Sexual dimorphism in the osmopressor response following water ingestion
title_full Sexual dimorphism in the osmopressor response following water ingestion
title_fullStr Sexual dimorphism in the osmopressor response following water ingestion
title_full_unstemmed Sexual dimorphism in the osmopressor response following water ingestion
title_short Sexual dimorphism in the osmopressor response following water ingestion
title_sort sexual dimorphism in the osmopressor response following water ingestion
topic Original Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293556/
https://www.ncbi.nlm.nih.gov/pubmed/27129286
http://dx.doi.org/10.1042/BSR20150276
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