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Iron-chelating agent desferrioxamine stimulates formation of neutrophil extracellular traps (NETs) in human blood-derived neutrophils

Neutrophil extracellular trap (NET) formation is a significant innate immune defense mechanism against microbial infection that complements other neutrophil functions including phagocytosis and degranulation of antimicrobial peptides. NETs are decondensed chromatin structures in which antimicrobial...

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Detalles Bibliográficos
Autores principales: Völlger, Lena, Akong-Moore, Kathryn, Cox, Linda, Goldmann, Oliver, Wang, Yanming, Schäfer, Simon T., Naim, Hassan Y., Nizet, Victor, von Köckritz-Blickwede, Maren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293572/
https://www.ncbi.nlm.nih.gov/pubmed/27129288
http://dx.doi.org/10.1042/BSR20160031