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Leucine alleviates dexamethasone-induced suppression of muscle protein synthesis via synergy involvement of mTOR and AMPK pathways

Glucocorticoids (GCs) are negative muscle protein regulators that contribute to the whole-body catabolic state during stress. Mammalian target of rapamycin (mTOR)-signalling pathway, which acts as a central regulator of protein metabolism, can be activated by branched-chain amino acids (BCAA). In th...

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Detalles Bibliográficos
Autores principales: Wang, Xiao J., Yang, Xin, Wang, Ru X., Jiao, Hong C., Zhao, Jing P., Song, Zhi G., Lin, Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293580/
https://www.ncbi.nlm.nih.gov/pubmed/27129299
http://dx.doi.org/10.1042/BSR20160096