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Angiotensin type-2 (AT-2)-receptor activation reduces renal fibrosis in cyclosporine nephropathy: evidence for blood pressure independent effect

Compound 21 (C21), selective agonist of angiotensin type-2 (AT-2) receptors, shows anti-inflammatory effects in experimental models of hypertension and nephroprotection in diabetes. The aim of the present study was to evaluate the effects of C21 in cyclosporine nephropathy, which is characterized ma...

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Detalles Bibliográficos
Autores principales: Castoldi, Giovanna, di Gioia, Cira R.T., Carletti, Raffaella, Roma, Francesca, Zerbini, Gianpaolo, Stella, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293591/
https://www.ncbi.nlm.nih.gov/pubmed/27679859
http://dx.doi.org/10.1042/BSR20160278