Cargando…

Angiotensin type-2 (AT-2)-receptor activation reduces renal fibrosis in cyclosporine nephropathy: evidence for blood pressure independent effect

Compound 21 (C21), selective agonist of angiotensin type-2 (AT-2) receptors, shows anti-inflammatory effects in experimental models of hypertension and nephroprotection in diabetes. The aim of the present study was to evaluate the effects of C21 in cyclosporine nephropathy, which is characterized ma...

Descripción completa

Detalles Bibliográficos
Autores principales:	Castoldi, Giovanna, di Gioia, Cira R.T., Carletti, Raffaella, Roma, Francesca, Zerbini, Gianpaolo, Stella, Andrea
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2016
Materias:	Original Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293591/ https://www.ncbi.nlm.nih.gov/pubmed/27679859 http://dx.doi.org/10.1042/BSR20160278

Ejemplares similares

Sodium-glucose cotransporter 2 inhibition prevents renal fibrosis in cyclosporine nephropathy
por: Castoldi, Giovanna, et al.
Publicado: (2021)

Angiotensin Type 2 and Mas Receptor Activation Prevents Myocardial Fibrosis and Hypertrophy through the Reduction of Inflammatory Cell Infiltration and Local Sympathetic Activity in Angiotensin II-Dependent Hypertension
por: Castoldi, Giovanna, et al.
Publicado: (2021)

Cardioprotective Effects of Sodium Glucose Cotransporter 2 Inhibition in Angiotensin II-Dependent Hypertension Are Mediated by the Local Reduction of Sympathetic Activity and Inflammation
por: Castoldi, Giovanna, et al.
Publicado: (2023)

Angiotensin II Modulates Calcium/Phosphate Excretion in Experimental Model of Hypertension: Focus on Bone
por: Castoldi, Giovanna, et al.
Publicado: (2022)

Thoracic Aorta: Anatomy and Pathology
por: di Gioia, Cira Rosaria Tiziana, et al.
Publicado: (2023)

Effects of Cyclosporin A Therapy Combined with Steroids and Angiotensin Converting Enzyme Inhibitors on Childhood IgA Nephropathy
por: Shin, Jae Il, et al.
Publicado: (2010)

Delayed treatment with oleanolic acid attenuates tubulointerstitial fibrosis in chronic cyclosporine nephropathy through Nrf2/HO-1 signaling
por: Hong, Yu Ah, et al.
Publicado: (2014)

Histomorphological and inflammatory changes of white adipose tissue in gastrointestinal cancer patients with and without cachexia
por: Molfino, Alessio, et al.
Publicado: (2021)

Established and Newly Proposed Mechanisms of Chronic Cyclosporine Nephropathy
por: Yoon, Hye Eun, et al.
Publicado: (2009)

Loss of Function SETD2 Mutations in Poorly Differentiated Metastases from Two Hürthle Cell Carcinomas of the Thyroid
por: Pecce, Valeria, et al.
Publicado: (2020)

HbA(1c) Variability as an Independent Correlate of Nephropathy, but Not Retinopathy, in Patients With Type 2 Diabetes: The Renal Insufficiency And Cardiovascular Events (RIACE) Italian Multicenter Study
por: Penno, Giuseppe, et al.
Publicado: (2013)

Subtotal resection of vestibular schwannoma: Evaluation with Ki-67 measurement, magnetic resonance imaging, and long-term observation
por: Iannella, Giannicola, et al.
Publicado: (2017)

Evaluation of Merkel Cell Polyomavirus DNA in Tissue Samples from Italian Patients with Diagnosis of MCC
por: Prezioso, Carla, et al.
Publicado: (2021)

Lysyl oxidase inhibitors attenuate cyclosporin A-induced nephropathy in mouse
por: Nguyen, Long T., et al.
Publicado: (2021)

Histological Effects of an Innovative 445 Nm Blue Laser During Oral Soft Tissue Biopsy
por: Palaia, Gaspare, et al.
Publicado: (2020)

Angiotensin II Contributes to Renal Fibrosis Independently of Notch Pathway Activation
por: Lavoz, Carolina, et al.
Publicado: (2012)

Angiotensin converting enzyme gene polymorphism in type 2 diabetics with nephropathy
por: Naresh, V. V. S., et al.
Publicado: (2010)

Comparison of Early and Late Conversion of Sirolimus in Experimental Model of Chronic Cyclosporine Nephropathy
por: Kim, Jin Young, et al.
Publicado: (2012)

Membranous Nephropathy: Pilot Study of a Novel Regimen Combining Cyclosporine and Rituximab
por: Waldman, Meryl, et al.
Publicado: (2016)

Efficacy and safety of cyclosporine A in the treatment of idiopathic membranous nephropathy in an Asian population
por: Lin, Shujun, et al.
Publicado: (2019)

A review of urinary angiotensin converting enzyme 2 in diabetes and diabetic nephropathy
por: Gilbert, Akankwasa, et al.
Publicado: (2018)

Low-dose cyclosporine in treatment of membranous nephropathy with nephrotic syndrome: effectiveness and renal safety
por: Yu, Xiaojuan, et al.
Publicado: (2017)

Cyclosporine A-Induced Conchal Hyperplasia with Nasal Obstruction in a Patient with Membranous Nephropathy
por: Tillmann, Frank-Peter, et al.
Publicado: (2022)

Dual deficiency of angiotensin‐converting enzyme‐2 and Mas receptor enhances angiotensin II‐induced hypertension and hypertensive nephropathy
por: Ni, Jun, et al.
Publicado: (2020)

Evaluation of Browning Markers in Subcutaneous Adipose Tissue of Newly Diagnosed Gastrointestinal Cancer Patients with and without Cachexia
por: Molfino, Alessio, et al.
Publicado: (2022)

The effects of A(2B) receptor modulators on vascular endothelial growth factor and nitric oxide axis in chronic cyclosporine nephropathy
por: Patel, Leena, et al.
Publicado: (2015)

Effect of Cyclosporin A and Angiotensin II on cytosolic calcium levels in primary human gingival fibroblasts
por: Supraja, Ajitkumar, et al.
Publicado: (2016)

Stimulation of Angiotensin Converting Enzyme 2: A Novel Treatment Strategy for Diabetic Nephropathy
por: Nomura, Haru, et al.
Publicado: (2022)

Induction of PPAR Gamma mRNA and Protein Expression by Rosiglitazone in Chronic Cyclosporine Nephropathy in the Rat
por: Ahn, Kyung Ohk, et al.
Publicado: (2007)

Stepwise Treatment Using Corticosteroids Alone and in Combination with Cyclosporine in Korean Patients with Idiopathic Membranous Nephropathy
por: Shin, Dong Ho, et al.
Publicado: (2013)

Angiotensin II Type II Receptor Deficiency Accelerates the Development of Nephropathy in Type I Diabetes via Oxidative Stress and ACE2
por: Chang, Shiao-Ying, et al.
Publicado: (2011)

Is the Antiproteinuric Effect of Cyclosporine A Independent of Its Immunosuppressive Function in T Cells?
por: Zhang, Bin, et al.
Publicado: (2012)

Upregulation of hepatic angiotensin-converting enzyme 2 (ACE2) and angiotensin-(1–7) levels in experimental biliary fibrosis()
por: Herath, Chandana B., et al.
Publicado: (2007)

The mineralocorticoid receptor antagonist eplerenone reduces renal interstitial fibrosis after long-term cyclosporine treatment in rat: antagonizing cyclosporine nephrotoxicity
por: Nielsen, Finn Thomsen, et al.
Publicado: (2013)

Significance of combined cyclosporine−prednisolone therapy and cyclosporine blood concentration monitoring for idiopathic membranous nephropathy with steroid-resistant nephrotic syndrome: a randomized controlled multicenter trial
por: Saito, Takao, et al.
Publicado: (2013)

Stillbirth and fetal capillary infection by SARS-CoV-2
por: di Gioia, Cira, et al.
Publicado: (2022)

Dual Blockade of the Renin-Angiotensin System in Diabetic Nephropathy
por: Ravid, Mordchai
Publicado: (2009)

Economic evaluations of angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers in type 2 diabetic nephropathy: a systematic review
por: Huang, Yunyu, et al.
Publicado: (2014)

Efficacy and Safety of 0.1% Cyclosporine versus 2% Cyclosporine in the Treatment of Severe Vernal Keratoconjunctivitis in Children
por: Bourcier, Tristan, et al.
Publicado: (2022)

Podocyte-specific overexpression of human angiotensin-converting enzyme 2 attenuates diabetic nephropathy in mice
por: Nadarajah, Renisha, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_pb002o64jrfqofc80h0sd7nm3k