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Heterogeneity of tumor cells in terms of cancer-initiating cells
Tumors derive from a single cell clone but consist of heterogeneous cell subpopulations with diverse features and functions. A limited number of subclones with a selective advantage can initiate tumors when inoculated into immunocompromised mice, and are called cancer-initiating cells (CICs). CICs c...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Japanese Society of Toxicologic Pathology
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293686/ https://www.ncbi.nlm.nih.gov/pubmed/28190919 http://dx.doi.org/10.1293/tox.2016-0056 |