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Cost-utility analysis of dynamic intraligamentary stabilization versus early reconstruction after rupture of the anterior cruciate ligament

OBJECTIVES: The aim of this study was to evaluate the cost-effectiveness of the dynamic intraligamentary stabilization (DIS) technique in comparison with reconstructive surgery (ACLR) in the treatment of isolated anterior cruciate ligament (ACL) ruptures from the perspective of the community of insu...

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Autores principales: Bierbaum, Martin, Schöffski, Oliver, Schliemann, Benedikt, Kösters, Clemens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293706/
https://www.ncbi.nlm.nih.gov/pubmed/28168633
http://dx.doi.org/10.1186/s13561-017-0143-9
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author Bierbaum, Martin
Schöffski, Oliver
Schliemann, Benedikt
Kösters, Clemens
author_facet Bierbaum, Martin
Schöffski, Oliver
Schliemann, Benedikt
Kösters, Clemens
author_sort Bierbaum, Martin
collection PubMed
description OBJECTIVES: The aim of this study was to evaluate the cost-effectiveness of the dynamic intraligamentary stabilization (DIS) technique in comparison with reconstructive surgery (ACLR) in the treatment of isolated anterior cruciate ligament (ACL) ruptures from the perspective of the community of insured citizens in Germany. METHODS: Because of the specific decision problem at hand, namely that with DIS the procedure has to take place within 21 days after the initial trauma, a decision tree was developed. The time horizon of the model was set to 3 years. Input data was taken from official tariffs, payer data, the literature and assumptions based on expert opinion when necessary. RESULTS: The decision tree analysis identified the DIS strategy as the superior one with 2.34 QALY versus 2.26 QALY for the ACLR branch. The higher QALY also came with higher costs of 5,398.05 € for the DIS branch versus 4,632.68 € for the ACLR branch respectively, leading to an ICER of 9,092.66 € per QALY. Results were robust after sensitivity analysis. Uncertainty was examined via probabilistic sensitivity analysis resulting in a slightly higher ICER of 9,567.13 € per QALY gained. CONCLUSION: The DIS technology delivers an effective treatment for the ACL rupture at a favorable incremental cost-effectiveness ratio. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13561-017-0143-9) contains supplementary material, which is available to authorized users.
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spelling pubmed-52937062017-02-21 Cost-utility analysis of dynamic intraligamentary stabilization versus early reconstruction after rupture of the anterior cruciate ligament Bierbaum, Martin Schöffski, Oliver Schliemann, Benedikt Kösters, Clemens Health Econ Rev Research OBJECTIVES: The aim of this study was to evaluate the cost-effectiveness of the dynamic intraligamentary stabilization (DIS) technique in comparison with reconstructive surgery (ACLR) in the treatment of isolated anterior cruciate ligament (ACL) ruptures from the perspective of the community of insured citizens in Germany. METHODS: Because of the specific decision problem at hand, namely that with DIS the procedure has to take place within 21 days after the initial trauma, a decision tree was developed. The time horizon of the model was set to 3 years. Input data was taken from official tariffs, payer data, the literature and assumptions based on expert opinion when necessary. RESULTS: The decision tree analysis identified the DIS strategy as the superior one with 2.34 QALY versus 2.26 QALY for the ACLR branch. The higher QALY also came with higher costs of 5,398.05 € for the DIS branch versus 4,632.68 € for the ACLR branch respectively, leading to an ICER of 9,092.66 € per QALY. Results were robust after sensitivity analysis. Uncertainty was examined via probabilistic sensitivity analysis resulting in a slightly higher ICER of 9,567.13 € per QALY gained. CONCLUSION: The DIS technology delivers an effective treatment for the ACL rupture at a favorable incremental cost-effectiveness ratio. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13561-017-0143-9) contains supplementary material, which is available to authorized users. Springer Berlin Heidelberg 2017-02-06 /pmc/articles/PMC5293706/ /pubmed/28168633 http://dx.doi.org/10.1186/s13561-017-0143-9 Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Research
Bierbaum, Martin
Schöffski, Oliver
Schliemann, Benedikt
Kösters, Clemens
Cost-utility analysis of dynamic intraligamentary stabilization versus early reconstruction after rupture of the anterior cruciate ligament
title Cost-utility analysis of dynamic intraligamentary stabilization versus early reconstruction after rupture of the anterior cruciate ligament
title_full Cost-utility analysis of dynamic intraligamentary stabilization versus early reconstruction after rupture of the anterior cruciate ligament
title_fullStr Cost-utility analysis of dynamic intraligamentary stabilization versus early reconstruction after rupture of the anterior cruciate ligament
title_full_unstemmed Cost-utility analysis of dynamic intraligamentary stabilization versus early reconstruction after rupture of the anterior cruciate ligament
title_short Cost-utility analysis of dynamic intraligamentary stabilization versus early reconstruction after rupture of the anterior cruciate ligament
title_sort cost-utility analysis of dynamic intraligamentary stabilization versus early reconstruction after rupture of the anterior cruciate ligament
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293706/
https://www.ncbi.nlm.nih.gov/pubmed/28168633
http://dx.doi.org/10.1186/s13561-017-0143-9
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