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Cost-utility analysis of dynamic intraligamentary stabilization versus early reconstruction after rupture of the anterior cruciate ligament
OBJECTIVES: The aim of this study was to evaluate the cost-effectiveness of the dynamic intraligamentary stabilization (DIS) technique in comparison with reconstructive surgery (ACLR) in the treatment of isolated anterior cruciate ligament (ACL) ruptures from the perspective of the community of insu...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293706/ https://www.ncbi.nlm.nih.gov/pubmed/28168633 http://dx.doi.org/10.1186/s13561-017-0143-9 |
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author | Bierbaum, Martin Schöffski, Oliver Schliemann, Benedikt Kösters, Clemens |
author_facet | Bierbaum, Martin Schöffski, Oliver Schliemann, Benedikt Kösters, Clemens |
author_sort | Bierbaum, Martin |
collection | PubMed |
description | OBJECTIVES: The aim of this study was to evaluate the cost-effectiveness of the dynamic intraligamentary stabilization (DIS) technique in comparison with reconstructive surgery (ACLR) in the treatment of isolated anterior cruciate ligament (ACL) ruptures from the perspective of the community of insured citizens in Germany. METHODS: Because of the specific decision problem at hand, namely that with DIS the procedure has to take place within 21 days after the initial trauma, a decision tree was developed. The time horizon of the model was set to 3 years. Input data was taken from official tariffs, payer data, the literature and assumptions based on expert opinion when necessary. RESULTS: The decision tree analysis identified the DIS strategy as the superior one with 2.34 QALY versus 2.26 QALY for the ACLR branch. The higher QALY also came with higher costs of 5,398.05 € for the DIS branch versus 4,632.68 € for the ACLR branch respectively, leading to an ICER of 9,092.66 € per QALY. Results were robust after sensitivity analysis. Uncertainty was examined via probabilistic sensitivity analysis resulting in a slightly higher ICER of 9,567.13 € per QALY gained. CONCLUSION: The DIS technology delivers an effective treatment for the ACL rupture at a favorable incremental cost-effectiveness ratio. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13561-017-0143-9) contains supplementary material, which is available to authorized users. |
format | Online Article Text |
id | pubmed-5293706 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-52937062017-02-21 Cost-utility analysis of dynamic intraligamentary stabilization versus early reconstruction after rupture of the anterior cruciate ligament Bierbaum, Martin Schöffski, Oliver Schliemann, Benedikt Kösters, Clemens Health Econ Rev Research OBJECTIVES: The aim of this study was to evaluate the cost-effectiveness of the dynamic intraligamentary stabilization (DIS) technique in comparison with reconstructive surgery (ACLR) in the treatment of isolated anterior cruciate ligament (ACL) ruptures from the perspective of the community of insured citizens in Germany. METHODS: Because of the specific decision problem at hand, namely that with DIS the procedure has to take place within 21 days after the initial trauma, a decision tree was developed. The time horizon of the model was set to 3 years. Input data was taken from official tariffs, payer data, the literature and assumptions based on expert opinion when necessary. RESULTS: The decision tree analysis identified the DIS strategy as the superior one with 2.34 QALY versus 2.26 QALY for the ACLR branch. The higher QALY also came with higher costs of 5,398.05 € for the DIS branch versus 4,632.68 € for the ACLR branch respectively, leading to an ICER of 9,092.66 € per QALY. Results were robust after sensitivity analysis. Uncertainty was examined via probabilistic sensitivity analysis resulting in a slightly higher ICER of 9,567.13 € per QALY gained. CONCLUSION: The DIS technology delivers an effective treatment for the ACL rupture at a favorable incremental cost-effectiveness ratio. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13561-017-0143-9) contains supplementary material, which is available to authorized users. Springer Berlin Heidelberg 2017-02-06 /pmc/articles/PMC5293706/ /pubmed/28168633 http://dx.doi.org/10.1186/s13561-017-0143-9 Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
spellingShingle | Research Bierbaum, Martin Schöffski, Oliver Schliemann, Benedikt Kösters, Clemens Cost-utility analysis of dynamic intraligamentary stabilization versus early reconstruction after rupture of the anterior cruciate ligament |
title | Cost-utility analysis of dynamic intraligamentary stabilization versus early reconstruction after rupture of the anterior cruciate ligament |
title_full | Cost-utility analysis of dynamic intraligamentary stabilization versus early reconstruction after rupture of the anterior cruciate ligament |
title_fullStr | Cost-utility analysis of dynamic intraligamentary stabilization versus early reconstruction after rupture of the anterior cruciate ligament |
title_full_unstemmed | Cost-utility analysis of dynamic intraligamentary stabilization versus early reconstruction after rupture of the anterior cruciate ligament |
title_short | Cost-utility analysis of dynamic intraligamentary stabilization versus early reconstruction after rupture of the anterior cruciate ligament |
title_sort | cost-utility analysis of dynamic intraligamentary stabilization versus early reconstruction after rupture of the anterior cruciate ligament |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293706/ https://www.ncbi.nlm.nih.gov/pubmed/28168633 http://dx.doi.org/10.1186/s13561-017-0143-9 |
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